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Calcium Signaling, PKC Gamma, IP(3)R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development

BACKGROUND: Spinocerebellar ataxias (SCAs) are a group of cerebellar diseases characterized by progressive ataxia and cerebellar atrophy. Several forms of SCAs are caused by missense mutations or deletions in genes related to calcium signaling in Purkinje cells. Among them, spinocerebellar ataxia ty...

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Publicat a:Curr Neuropharmacol
Autors principals: Shimobayashi, Etsuko, Kapfhammer, Josef P.
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883377/
https://ncbi.nlm.nih.gov/pubmed/28554312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X15666170529104000
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