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The embryonic transcription factor Brachyury confers chordoma chemoresistance via upregulating CA9

Being a rare malignant bone tumor on the axial skeleton, chordoma is locally invasive and has a high rate of recurrence. Despite extensive studies, the mechanisms of chordoma recurrence after surgical intervention, as well as resistance to radiation and chemotherapy, remain elusive. In this study, p...

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Vydáno v:Am J Transl Res
Hlavní autoři: Jian, Jiao, Zhong, Nanzhe, Jiang, Dongjie, Li, Lei, Lou, Yan, Zhou, Wang, Chen, Su, Xiao, Jianru
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883134/
https://ncbi.nlm.nih.gov/pubmed/29636883
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