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Cyclooxygenase-2 deficiency causes delayed ossification of lumbar vertebral endplates

Based on previous findings that cyclooxygenase-2 (COX-2) is a critical molecule in chondrocyte differentiation and skeletal repair, we hypothesized that COX-2 deficiency or inhibition affects the ossification of vertebral endplates (VEP) and degeneration of intervertebral discs (IVD) and thus is inv...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Ding, Qingfeng, Ren, Yongxin, Che, Hui, Ma, Cheng, Li, Huiwu, Yu, Suojing, Zhang, Yejia, An, Howard, O’Keefe, Regis J, Chen, Di, Block, Joel A, Yin, Guoyong, Li, Tianfang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883113/
https://ncbi.nlm.nih.gov/pubmed/29636862
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