Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells

Muscle atrophy is one of the main characteristics of human ageing and physical inactivity, with resulting adverse health outcomes. To date, there are still no efficient therapeutic strategies for its prevention and/or treatment. However, during hibernation, bears exhibit a unique ability for preserv...

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Wydane w:Sci Rep
Główni autorzy: Chanon, Stéphanie, Chazarin, Blandine, Toubhans, Benoit, Durand, Christine, Chery, Isabelle, Robert, Maud, Vieille-Marchiset, Aurélie, Swenson, Jon E., Zedrosser, Andreas, Evans, Alina L., Brunberg, Sven, Arnemo, Jon M., Gauquelin-Koch, Guillemette, Storey, Kenneth B., Simon, Chantal, Blanc, Stéphane, Bertile, Fabrice, Lefai, Etienne
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group UK 2018
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883044/
https://ncbi.nlm.nih.gov/pubmed/29615761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23891-5
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