Proteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells

Muscle atrophy is one of the main characteristics of human ageing and physical inactivity, with resulting adverse health outcomes. To date, there are still no efficient therapeutic strategies for its prevention and/or treatment. However, during hibernation, bears exhibit a unique ability for preserv...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Chanon, Stéphanie, Chazarin, Blandine, Toubhans, Benoit, Durand, Christine, Chery, Isabelle, Robert, Maud, Vieille-Marchiset, Aurélie, Swenson, Jon E., Zedrosser, Andreas, Evans, Alina L., Brunberg, Sven, Arnemo, Jon M., Gauquelin-Koch, Guillemette, Storey, Kenneth B., Simon, Chantal, Blanc, Stéphane, Bertile, Fabrice, Lefai, Etienne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883044/
https://ncbi.nlm.nih.gov/pubmed/29615761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23891-5
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