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Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose

Vaccines offer an option to treat heroin and prescription opioid abuse and prevent fatal overdoses. Opioid vaccines elicit antibodies that block opioid distribution to the brain and reduce opioid-induced behavioral effects and toxicity. The major limitation to the translation of addiction vaccines i...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Laudenbach, Megan, Baruffaldi, Federico, Robinson, Christine, Carter, Philipp, Seelig, Davis, Baehr, Carly, Pravetoni, Marco
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882912/
https://ncbi.nlm.nih.gov/pubmed/29615715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23777-6
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