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Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose

Vaccines offer an option to treat heroin and prescription opioid abuse and prevent fatal overdoses. Opioid vaccines elicit antibodies that block opioid distribution to the brain and reduce opioid-induced behavioral effects and toxicity. The major limitation to the translation of addiction vaccines i...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Laudenbach, Megan, Baruffaldi, Federico, Robinson, Christine, Carter, Philipp, Seelig, Davis, Baehr, Carly, Pravetoni, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882912/
https://ncbi.nlm.nih.gov/pubmed/29615715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23777-6
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