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Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose

Vaccines offer an option to treat heroin and prescription opioid abuse and prevent fatal overdoses. Opioid vaccines elicit antibodies that block opioid distribution to the brain and reduce opioid-induced behavioral effects and toxicity. The major limitation to the translation of addiction vaccines i...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Laudenbach, Megan, Baruffaldi, Federico, Robinson, Christine, Carter, Philipp, Seelig, Davis, Baehr, Carly, Pravetoni, Marco
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882912/
https://ncbi.nlm.nih.gov/pubmed/29615715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23777-6
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