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Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma

The computational repositioning of existing drugs represents an appealing avenue for identifying effective compounds to treat diseases with no FDA-approved pharmacotherapies. Here we present the largest meta-analysis to date of differential gene expression in human vestibular schwannoma (VS), a debi...

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Pubblicato in:Sci Rep
Autori principali: Sagers, Jessica E., Brown, Adam S., Vasilijic, Sasa, Lewis, Rebecca M., Sahin, Mehmet I., Landegger, Lukas D., Perlis, Roy H., Kohane, Isaac S., Welling, D. Bradley, Patel, Chirag J., Stankovic, Konstantina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882888/
https://ncbi.nlm.nih.gov/pubmed/29615643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23609-7
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