Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma

The computational repositioning of existing drugs represents an appealing avenue for identifying effective compounds to treat diseases with no FDA-approved pharmacotherapies. Here we present the largest meta-analysis to date of differential gene expression in human vestibular schwannoma (VS), a debi...

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Udgivet i:Sci Rep
Main Authors: Sagers, Jessica E., Brown, Adam S., Vasilijic, Sasa, Lewis, Rebecca M., Sahin, Mehmet I., Landegger, Lukas D., Perlis, Roy H., Kohane, Isaac S., Welling, D. Bradley, Patel, Chirag J., Stankovic, Konstantina M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882888/
https://ncbi.nlm.nih.gov/pubmed/29615643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23609-7
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