Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension

Background: Hypertension is characterized by sympathetic overactivity, which is associated with an enhancement in angiotensin receptor type I (AT1R) in the rostral ventrolateral medulla (RVLM). β-arrestin1, a canonical scaffold protein, has been suggested to show a negative effect on G protein-coupl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Physiol
Hlavní autoři: Sun, Jia-Cen, Liu, Bing, Zhang, Ru-Wen, Jiao, Pei-Lei, Tan, Xing, Wang, Yang-Kai, Wang, Wei-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882868/
https://ncbi.nlm.nih.gov/pubmed/29643817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00297
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky