HMGB1 Increases IL-1β Production in Vascular Smooth Muscle Cells via NLRP3 Inflammasome

Vascular smooth muscle cells (VSMCs) are the major cell type in the blood vessel walls, and their phenotypic modulation is a key cellular event driving vascular remodeling. Although high mobility group box-1 (HMGB1) plays a pivotal role in inflammatory processes after vascular injuries, the importan...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Kim, Eun Jung, Park, So Youn, Baek, Seung Eun, Jang, Min A., Lee, Won Suk, Bae, Sun Sik, Kim, Koanhoi, Kim, Chi Dae
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882820/
https://ncbi.nlm.nih.gov/pubmed/29643819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00313
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