Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells

Etoposide (ETP) and anthracyclines are applied for wide anti-cancer treatments. However, the ETP-induced cardiotoxicity remains to be a major safety issue and the underlying cardiotoxic mechanisms are not well understood. This study is aiming to unravel the cardiotoxicity profile of ETP in compariso...

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Detalles Bibliográficos
Publicado en:Arch Toxicol
Main Authors: Nemade, Harshal, Chaudhari, Umesh, Acharya, Aviseka, Hescheler, Jürgen, Hengstler, Jan Georg, Papadopoulos, Symeon, Sachinidis, Agapios
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2018
Assuntos:
In Vitro Systems
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882643/
https://ncbi.nlm.nih.gov/pubmed/29397400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2170-7
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