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Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells

Etoposide (ETP) and anthracyclines are applied for wide anti-cancer treatments. However, the ETP-induced cardiotoxicity remains to be a major safety issue and the underlying cardiotoxic mechanisms are not well understood. This study is aiming to unravel the cardiotoxicity profile of ETP in compariso...

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Bibliografski detalji
Izdano u:Arch Toxicol
Glavni autori: Nemade, Harshal, Chaudhari, Umesh, Acharya, Aviseka, Hescheler, Jürgen, Hengstler, Jan Georg, Papadopoulos, Symeon, Sachinidis, Agapios
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882643/
https://ncbi.nlm.nih.gov/pubmed/29397400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2170-7
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