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Development of a Cell-Based Assay to Assess Binding of the proNGF Prodomain to Sortilin

Sortilin was first identified based on its activity as part of intracellular protein sorting machinery. Recently, it was discovered that sortilin also acts as a cell surface receptor for the propeptide form of nerve growth factor (proNGF), progranulin, and neurotensin. The interaction of sortilin to...

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Detalhes bibliográficos
Publicado no:Cell Mol Neurobiol
Main Authors: Malik, Ibrahim, Christensen, Søren, Stavenhagen, Jeffrey B., Dietz, Gunnar P. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882628/
https://ncbi.nlm.nih.gov/pubmed/29067536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-017-0558-1
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