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Clinical implications of the Hippo-YAP pathway in multiple cancer contexts
The Hippo pathway plays prominent and widespread roles in various forms of human carcinogenesis. Specifically, the Yes-associated protein (YAP), a downstream effector of the Hippo pathway, can lead to excessive cell proliferation and the inhibition of apoptosis, resulting in tumorigenesis. It was re...
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Veröffentlicht in: | BMB Rep |
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Hauptverfasser: | , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Korean Society for Biochemistry and Molecular Biology
2018
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5882218/ https://ncbi.nlm.nih.gov/pubmed/29366445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.3.018 |
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