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Clinical implications of the Hippo-YAP pathway in multiple cancer contexts

The Hippo pathway plays prominent and widespread roles in various forms of human carcinogenesis. Specifically, the Yes-associated protein (YAP), a downstream effector of the Hippo pathway, can lead to excessive cell proliferation and the inhibition of apoptosis, resulting in tumorigenesis. It was re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMB Rep
Hauptverfasser: Kim, Han-Byul, Myung, Seung-Jae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882218/
https://ncbi.nlm.nih.gov/pubmed/29366445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.3.018
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