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Free energy calculations on the stability of the 14-3-3ζ protein

Mutations of cysteine are often introduced to e.g. avoid formation of non-physiological inter-molecular disulfide bridges in in-vitro experiments, or to maintain specificity in labeling experiments. Alanine or serine is typically preferred, which usually do not alter the overall protein stability, w...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Jandova, Zuzana, Trosanova, Zuzana, Weisova, Veronika, Oostenbrink, Chris, Hritz, Jozef
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881884/
https://ncbi.nlm.nih.gov/pubmed/29203375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2017.11.012
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