Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats

Glucocorticoids (GCs) are the most common cause of atraumatic osteonecrosis of the femoral head (ONFH) because their effect compromises the osteogenic capability of bone marrow-derived mesenchymal stem cells (BMSCs). Valproic acid (VPA) is a widely used anti-epileptic and anticonvulsant drug. Previo...

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Bibliographic Details
Published in:Int J Mol Med
Main Authors: Zhou, Ding, Chen, Yi-Xuan, Yin, Jun-Hui, Tao, Shi-Cong, Guo, Shang-Chun, Wei, Zhan-Ying, Feng, Yong, Zhang, Chang-Qing
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881807/
https://ncbi.nlm.nih.gov/pubmed/29512684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3534
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