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Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications
BACKGROUND AND AIMS: Intestinal fibrosis is a frequent complication in Crohn’s disease [CD]. The mouse Salmonella typhimurium model, due to its simplicity, reproducibility, manipulability, and penetrance, is an established fibrosis model for drug discovery and preclinical trials. However, the severi...
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| Veröffentlicht in: | J Crohns Colitis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881735/ https://ncbi.nlm.nih.gov/pubmed/27986839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw210 |
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