Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells

Infection with Helicobacter pylori is known to decrease the level of glutathione in gastric epithelial cells and increase the production of reactive oxygen species (ROS), which can lead to DNA damage and the development of gastric cancer. Cation transport regulator 1 (CHAC1) has γ‐glutamylcyclotrans...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Open Bio
Prif Awduron: Wada, Yuriko, Takemura, Kosuke, Tummala, Padmaja, Uchida, Keisuke, Kitagaki, Keisuke, Furukawa, Asuka, Ishige, Yuuki, Ito, Takashi, Hara, Yukichi, Suzuki, Takashige, Mimuro, Hitomi, Board, Philip G., Eishi, Yoshinobu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881537/
https://ncbi.nlm.nih.gov/pubmed/29632819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12402
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