In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitro-conjugated linoleic acid (NO(2)-CLA). Herein, NO(2)-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Villacorta, Luis, Minarrieta, Lucia, Salvatore, Sonia R., Khoo, Nicholas K., Rom, Oren, Gao, Zhen, Berman, Rebecca C., Jobbagy, Soma, Li, Lihua, Woodcock, Steven R., Chen, Y. Eugene, Freeman, Bruce A., Ferreira, Ana M., Schopfer, Francisco J., Vitturi, Dario A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881417/
https://ncbi.nlm.nih.gov/pubmed/29413964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.01.005
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