In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitro-conjugated linoleic acid (NO(2)-CLA). Herein, NO(2)-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation...

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Udgivet i:Redox Biol
Main Authors: Villacorta, Luis, Minarrieta, Lucia, Salvatore, Sonia R., Khoo, Nicholas K., Rom, Oren, Gao, Zhen, Berman, Rebecca C., Jobbagy, Soma, Li, Lihua, Woodcock, Steven R., Chen, Y. Eugene, Freeman, Bruce A., Ferreira, Ana M., Schopfer, Francisco J., Vitturi, Dario A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881417/
https://ncbi.nlm.nih.gov/pubmed/29413964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.01.005
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