In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitro-conjugated linoleic acid (NO(2)-CLA). Herein, NO(2)-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation...

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Publicado en:Redox Biol
Autores principales: Villacorta, Luis, Minarrieta, Lucia, Salvatore, Sonia R., Khoo, Nicholas K., Rom, Oren, Gao, Zhen, Berman, Rebecca C., Jobbagy, Soma, Li, Lihua, Woodcock, Steven R., Chen, Y. Eugene, Freeman, Bruce A., Ferreira, Ana M., Schopfer, Francisco J., Vitturi, Dario A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881417/
https://ncbi.nlm.nih.gov/pubmed/29413964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.01.005
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