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New discoveries of extrachromosomal circles of DNA in normal and tumor cells

While the vast majority of cellular DNA in eukaryotes is contained in long linear strands in chromosomes, we have long recognized some exceptions like mitochondrial DNA, plasmids in yeasts and double-minutes in cancer cells where the DNA is present in extrachromosomal circles. In addition, specializ...

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Bibliographic Details
Published in:Trends Genet
Main Authors: Paulsen, Teressa, Kumar, Pankaj, Koseoglu, M. Murat, Dutta, Anindya
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881399/
https://ncbi.nlm.nih.gov/pubmed/29329720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.12.010
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