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The Tripod for Bacterial Natural Product Discovery: Genome Mining, Silent Pathway Induction, and Mass Spectrometry-Based Molecular Networking

Natural products are the richest source of chemical compounds for drug discovery. Particularly, bacterial secondary metabolites are in the spotlight due to advances in genome sequencing and mining, as well as for the potential of biosynthetic pathway manipulation to awake silent (cryptic) gene clust...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Trivella, Daniela B. B., de Felicio, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881025/
https://ncbi.nlm.nih.gov/pubmed/29629418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00160-17
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