Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling

Cellular activation in trans by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with inflammation is limited. This may be particu...

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Publicat a:Front Immunol
Autors principals: Moyo, Daniel, Beattie, Lynette, Andrews, Paul S., Moore, John W. J., Timmis, Jon, Sawtell, Amy, Hoehme, Stefan, Sampson, Adam T., Kaye, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880939/
https://ncbi.nlm.nih.gov/pubmed/29636754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00637
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