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Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling

Cellular activation in trans by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with inflammation is limited. This may be particu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Moyo, Daniel, Beattie, Lynette, Andrews, Paul S., Moore, John W. J., Timmis, Jon, Sawtell, Amy, Hoehme, Stefan, Sampson, Adam T., Kaye, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880939/
https://ncbi.nlm.nih.gov/pubmed/29636754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00637
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