High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes

The overwhelming majority of patients with chronic kidney disease (CKD) die prematurely before reaching end‐stage renal disease, mainly due to cardiovascular causes, of which heart failure is the predominant clinical presentation. We hypothesized that CKD‐induced increases of plasma FGF23 impair car...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Verkaik, Melissa, Oranje, Maarten, Abdurrachim, Desiree, Goebel, Max, Gam, Zeineb, Prompers, Jeanine J., Helmes, Michiel, ter Wee, Pieter M., van der Velden, Jolanda, Kuster, Diederik W., Vervloet, Marc G., Eringa, Etto C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880876/
https://ncbi.nlm.nih.gov/pubmed/29611320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13591
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