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Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance

OBJECTIVE: Resistance at the brain receptors for leptin and insulin has been associated with increased feeding, obesity and cognitive impairments. The causal agent for central resistance is unknown but could be derived from the blood. Here we postulate whether hypertriglyceridemia, the major dyslipi...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Banks, W A, Farr, S A, Salameh, T S, Niehoff, M L, Rhea, E M, Morley, J E, Hanson, A J, Hansen, K M, Craft, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880581/
https://ncbi.nlm.nih.gov/pubmed/28990588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2017.231
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