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Δ(9)-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation

Phytocannabinoids, such as Δ(9)-tetrahydrocannabinol (THC), bind and activate cannabinoid (CB) receptors, thereby “piggy-backing” on the same pathway’s endogenous endocannabinoids (ECs). The recent discovery that liver fatty acid binding protein-1 (FABP1) is the major cytosolic “chaperone” protein w...

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Bibliografske podrobnosti
izdano v:J Lipid Res
Main Authors: McIntosh, Avery L., Martin, Gregory G., Huang, Huan, Landrock, Danilo, Kier, Ann B., Schroeder, Friedhelm
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880504/
https://ncbi.nlm.nih.gov/pubmed/29414765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082644
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