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Modulation of nitric oxide bioavailability by erythrocytes

Nitric oxide (NO) activates soluble guanylyl cyclase in smooth muscle cells to induce vasodilation in the vasculature. However, as hemoglobin (Hb) is an effective scavenger of NO and is present in high concentrations inside the red blood cell (RBC), the bioavailability of NO would be too low to elic...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Huang, Kuang-Tse, Han, Tae H., Hyduke, Daniel R., Vaughn, Mark W., Van Herle, Helga, Hein, Travis W., Zhang, Cuihua, Kuo, Lih, Liao, James C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58805/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11573011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.201276698
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