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Modulation of nitric oxide bioavailability by erythrocytes

Nitric oxide (NO) activates soluble guanylyl cyclase in smooth muscle cells to induce vasodilation in the vasculature. However, as hemoglobin (Hb) is an effective scavenger of NO and is present in high concentrations inside the red blood cell (RBC), the bioavailability of NO would be too low to elic...

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Hlavní autoři: Huang, Kuang-Tse, Han, Tae H., Hyduke, Daniel R., Vaughn, Mark W., Van Herle, Helga, Hein, Travis W., Zhang, Cuihua, Kuo, Lih, Liao, James C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC58805/
https://ncbi.nlm.nih.gov/pubmed/11573011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201276698
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