Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing

Next-generation sequencing (NGS) efforts have established catalogs of mutations relevant to cancer development. However, the clinical utility of this information remains largely unexplored. Here, we present the results of the first eight patients recruited into a clinical whole-genome sequencing (WG...

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Publicado en:Cold Spring Harb Mol Case Stud
Autores principales: Schuh, Anna, Dreau, Helene, Knight, Samantha J.L., Ridout, Kate, Mizani, Tuba, Vavoulis, Dimitris, Colling, Richard, Antoniou, Pavlos, Kvikstad, Erika M., Pentony, Melissa M., Hamblin, Angela, Protheroe, Andrew, Parton, Marina, Shah, Ketan A., Orosz, Zsolt, Athanasou, Nick, Hassan, Bass, Flanagan, Adrienne M., Ahmed, Ahmed, Winter, Stuart, Harris, Adrian, Tomlinson, Ian, Popitsch, Niko, Church, David, Taylor, Jenny C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880257/
https://ncbi.nlm.nih.gov/pubmed/29610388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a002279
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