Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11 topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic chromosomes, with hotspots controlled by chromatin and DNA sequence. To map meiotic DSBs throughout a plant genome, we purif...

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Vydáno v:Genome Res
Hlavní autoři: Choi, Kyuha, Zhao, Xiaohui, Tock, Andrew J., Lambing, Christophe, Underwood, Charles J., Hardcastle, Thomas J., Serra, Heïdi, Kim, Juhyun, Cho, Hyun Seob, Kim, Jaeil, Ziolkowski, Piotr A., Yelina, Nataliya E., Hwang, Ildoo, Martienssen, Robert A., Henderson, Ian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880243/
https://ncbi.nlm.nih.gov/pubmed/29530928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.225599.117
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