Arabidopsis meiotic crossover hotspots overlap with H2A.Z nucleosomes at gene promoters

PRDM9 directs human meiotic crossover hotspots to intergenic sequence motifs, whereas budding yeast hotspots overlap low nucleosome density regions in gene promoters. To investigate hotspots in plants, which lack PRDM9, we used coalescent analysis of Arabidopsis genetic variation. Crossovers increas...

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Bibliografski detalji
Glavni autori: Choi, Kyuha, Zhao, Xiaohui, Kelly, Krystyna A., Venn, Oliver, Higgins, James D., Yelina, Nataliya E., Hardcastle, Thomas J., Ziolkowski, Piotr A., Copenhaver, Gregory P., Franklin, F. Chris H., McVean, Gil, Henderson, Ian R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812125/
https://ncbi.nlm.nih.gov/pubmed/24056716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2766
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