Arabidopsis meiotic crossover hotspots overlap with H2A.Z nucleosomes at gene promoters

PRDM9 directs human meiotic crossover hotspots to intergenic sequence motifs, whereas budding yeast hotspots overlap low nucleosome density regions in gene promoters. To investigate hotspots in plants, which lack PRDM9, we used coalescent analysis of Arabidopsis genetic variation. Crossovers increas...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Choi, Kyuha, Zhao, Xiaohui, Kelly, Krystyna A., Venn, Oliver, Higgins, James D., Yelina, Nataliya E., Hardcastle, Thomas J., Ziolkowski, Piotr A., Copenhaver, Gregory P., Franklin, F. Chris H., McVean, Gil, Henderson, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812125/
https://ncbi.nlm.nih.gov/pubmed/24056716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2766
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares