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Genome-wide determinants of sequence-specific DNA binding of general regulatory factors

General regulatory factors (GRFs), such as Reb1, Abf1, Rap1, Mcm1, and Cbf1, positionally organize yeast chromatin through interactions with a core consensus DNA sequence. It is assumed that sequence recognition via direct base readout suffices for specificity and that spurious nonfunctional sites a...

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Bibliographic Details
Published in:Genome Res
Main Authors: Rossi, Matthew J., Lai, William K.M., Pugh, B. Franklin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880240/
https://ncbi.nlm.nih.gov/pubmed/29563167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.229518.117
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