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Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice

Hepatocyte apoptosis has been implicated in the progression of nonalcoholic steatohepatitis. However, it is unclear whether the induction of tumor necrosis factor (TNF)‐α‐mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. To address this question, high‐fat diet‐fed mice...

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Библиографические подробности
Опубликовано в: :Hepatol Commun
Главные авторы: Osawa, Yosuke, Kojika, Ekumi, Hayashi, Yukiko, Kimura, Masamichi, Nishikawa, Koji, Yoshio, Sachiyo, Doi, Hiroyoshi, Kanto, Tatsuya, Kimura, Kiminori
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880193/
https://ncbi.nlm.nih.gov/pubmed/29619419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1158
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