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Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice

Hepatocyte apoptosis has been implicated in the progression of nonalcoholic steatohepatitis. However, it is unclear whether the induction of tumor necrosis factor (TNF)‐α‐mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. To address this question, high‐fat diet‐fed mice...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Osawa, Yosuke, Kojika, Ekumi, Hayashi, Yukiko, Kimura, Masamichi, Nishikawa, Koji, Yoshio, Sachiyo, Doi, Hiroyoshi, Kanto, Tatsuya, Kimura, Kiminori
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880193/
https://ncbi.nlm.nih.gov/pubmed/29619419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1158
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