Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice

Hepatocyte apoptosis has been implicated in the progression of nonalcoholic steatohepatitis. However, it is unclear whether the induction of tumor necrosis factor (TNF)‐α‐mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. To address this question, high‐fat diet‐fed mice...

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Publicado en:Hepatol Commun
Autores principales: Osawa, Yosuke, Kojika, Ekumi, Hayashi, Yukiko, Kimura, Masamichi, Nishikawa, Koji, Yoshio, Sachiyo, Doi, Hiroyoshi, Kanto, Tatsuya, Kimura, Kiminori
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880193/
https://ncbi.nlm.nih.gov/pubmed/29619419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1158
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