Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC)

The interpatient variability of tumor proteomes has been investigated on a large scale but many tumors display also intratumoral heterogeneity regarding morphological and genetic features. It remains largely unknown to what extent the local proteome of tumors intrinsically differs. Here, we used hep...

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Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Buczak, Katarzyna, Ori, Alessandro, Kirkpatrick, Joanna M., Holzer, Kerstin, Dauch, Daniel, Roessler, Stephanie, Endris, Volker, Lasitschka, Felix, Parca, Luca, Schmidt, Alexander, Zender, Lars, Schirmacher, Peter, Krijgsveld, Jeroen, Singer, Stephan, Beck, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880102/
https://ncbi.nlm.nih.gov/pubmed/29363612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000189
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