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Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury

Ischemic brain injury triggers neuronal cell death by apoptosis via caspase activation and by necroptosis through activation of the receptor-interacting protein kinases (RIPK) associated with the tumor necrosis factor-alpha (TNF-α)/death receptor. Recent evidence shows RIPK inhibitors are neuroprote...

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Dades bibliogràfiques
Publicat a:Neural Regen Res
Autors principals: Cruz, Shelly A., Qin, Zhaohong, Stewart, Alexandre F.R., Chen, Hsiao-Huei
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879896/
https://ncbi.nlm.nih.gov/pubmed/29557374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.226394
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