No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction

BACKGROUND: Chronic kidney disease (CKD) is characterized by sustained tissue damage and ongoing tubulo-interstitial inflammation and fibrosis. Pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) and NOD-like receptors (NLRs) can sense endogenous ligands released upon tissue da...

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Udgivet i:BMC Nephrol
Main Authors: Stroo, Ingrid, Emal, Diba, Butter, Loes M., Teske, Gwen J., Claessen, Nike, Dessing, Mark C., Girardin, Stephen E., Florquin, Sandrine, Leemans, Jaklien C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879837/
https://ncbi.nlm.nih.gov/pubmed/29609537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-018-0867-8
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