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Mathematical modelling of interacting mechanisms for hypoxia mediated cell cycle commitment for mesenchymal stromal cells

BACKGROUND: Existing experimental data have shown hypoxia to be an important factor affecting the proliferation of mesenchymal stromal cells (MSCs), but the contrasting observations made at various hypoxic levels raise the questions of whether hypoxia accelerates proliferation, and how. On the other...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Zhang, Bo, Ye, Hua, Yang, Aidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879778/
https://ncbi.nlm.nih.gov/pubmed/29606139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0560-3
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