SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT

BACKGROUND: Despite SGK1 has been identified and characterized as a tumor-promoting gene, the functions and underlying mechanisms of SGK1 involved in metastasis regulation have not yet been investigated in cancer. METHODS: We investigated the cellular responses to GSK650394 treatment and SGK1 silenc...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Liu, Weiwei, Wang, Xuchu, Wang, Yiyun, Dai, Yibei, Xie, Yiyi, Ping, Ying, Yin, Binbin, Yu, Pan, Liu, Zhenping, Duan, Xiuzhi, Liao, Zhaoping, Chen, Yuhua, Liu, Chunhua, Li, Xiang, Tao, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879613/
https://ncbi.nlm.nih.gov/pubmed/29609629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0743-1
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