53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress

Complete replication of the genome is an essential prerequisite for normal cell division, but a variety of factors can block the replisome, triggering replication stress and potentially causing mutation or cell death. The cellular response to replication stress involves recruitment of proteins to st...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Her, Joonyoung, Ray, Chandni, Altshuler, Jake, Zheng, Haiyan, Bunting, Samuel F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879462/
https://ncbi.nlm.nih.gov/pubmed/29378830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00472-17
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