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53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress
Complete replication of the genome is an essential prerequisite for normal cell division, but a variety of factors can block the replisome, triggering replication stress and potentially causing mutation or cell death. The cellular response to replication stress involves recruitment of proteins to st...
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Publicado no: | Mol Cell Biol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5879462/ https://ncbi.nlm.nih.gov/pubmed/29378830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00472-17 |
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