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MafB Is Critical for Glucagon Production and Secretion in Mouse Pancreatic α Cells In Vivo

The MafB transcription factor is expressed in pancreatic α and β cells during development but becomes exclusive to α cells in adult rodents. Mafb-null (Mafb(−/−)) mice were reported to have reduced α- and β-cell numbers throughout embryonic development. To further analyze the postnatal function of M...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Katoh, Megumi C., Jung, Yunshin, Ugboma, Chioma M., Shimbo, Miki, Kuno, Akihiro, Basha, Walaa A., Kudo, Takashi, Oishi, Hisashi, Takahashi, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879460/
https://ncbi.nlm.nih.gov/pubmed/29378833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00504-17
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