Uncovering the role of MAFB in glucagon production and secretion in pancreatic α-cells using a new α-cell-specific Mafb conditional knockout mouse model

Cre/loxP is a site-specific recombination system extensively used to enable the conditional deletion or activation of target genes in a spatial- and/or temporal-specific manner. A number of pancreatic-specific Cre driver mouse lines have been broadly established for studying the development, functio...

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Vydáno v:Exp Anim
Hlavní autoři: Chang, Yu-Hsin, Katoh, Megumi C., Abdellatif, Ahmed M., Xiafukaiti, Guli, Elzeftawy, Abdelaziz, Ojima, Masami, Mizuno, Seiya, Kuno, Akihiro, Takahashi, Satoru
Médium: Artigo
Jazyk:Inglês
Vydáno: Japanese Association for Laboratory Animal Science 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220711/
https://ncbi.nlm.nih.gov/pubmed/31787710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.19-0105
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