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Naïve CD4 T cells inhibit CD28-costimulated R5 HIV replication in memory CD4 T cells

Stimulation with antibodies to CD3 and CD28 coimmobilized on beads can be used to significantly expand T cells ex vivo. With CD4 T cells from HIV-infected patients, this expansion usually is accompanied by complete suppression of viral replication, presumed to be caused by down-regulation of the vir...

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Autors principals: Mengozzi, Manuela, Malipatlolla, Meena, De Rosa, Stephen C., Herzenberg, Leonard A., Herzenberg, Leonore A., Roederer, Mario
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58783/
https://ncbi.nlm.nih.gov/pubmed/11562498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211205098
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