Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy

AIMS/HYPOTHESIS: Our earlier studies have established the role of 12/15-lipoxygenase (LO) in mediating the inflammatory reaction in diabetic retinopathy. However, the exact mechanism is still unclear. The goal of the current study was to identify the potential role of endoplasmic reticulum (ER) stre...

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Veröffentlicht in:Diabetologia
Hauptverfasser: Elmasry, Khaled, Ibrahim, Ahmed S., Saleh, Heba, Elsherbiny, Nehal, Elshafey, Sally, Hussein, Khaled A., Al-Shabrawey, Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878142/
https://ncbi.nlm.nih.gov/pubmed/29468369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4560-z
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