Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury

Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Neuronal apoptosis in the hippocampus has been detected after TBI. The hippocampal dysfunction may result in cognitive deficits in learning, memory, and spatial information processing. Our previous studies demonstrated...

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Publicado no:Neurobiol Dis
Main Authors: Yang, Ling-Yu, Greig, Nigel H., Huang, Ya-Ni, Hsieh, Tsung-Hsun, Tweedie, David, Yu, Qian-Sheng, Hoffer, Barry J., Luo, Yu, Kao, Yu-Chieh, Wang, Jia-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878046/
https://ncbi.nlm.nih.gov/pubmed/27553877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.08.012
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