Role of glutathione metabolism in host defense against Borrelia burgdorferi infection

Pathogen-induced changes in host cell metabolism are known to be important for the immune response. In this study, we investigated how infection with the Lyme disease-causing bacterium Borrelia burgdorferi (Bb) affects host metabolic pathways and how these metabolic pathways may impact host defense....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kerstholt, Mariska, Vrijmoeth, Hedwig, Lachmandas, Ekta, Oosting, Marije, Lupse, Mihaela, Flonta, Mirela, Dinarello, Charles A., Netea, Mihai G., Joosten, Leo A. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877983/
https://ncbi.nlm.nih.gov/pubmed/29444855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720833115
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