Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy

A subset of patients with metastatic melanoma have sustained remissions following treatment with immune checkpoint inhibitors. However, analyses of pretreatment tumor biopsies for markers predictive of response, including PD-1 ligand (PD-L1) expression and mutational burden, are insufficiently preci...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Hong, Xin, Sullivan, Ryan J., Kalinich, Mark, Kwan, Tanya Todorova, Giobbie-Hurder, Anita, Pan, Shiwei, LiCausi, Joseph A., Milner, John D., Nieman, Linda T., Wittner, Ben S., Ho, Uyen, Chen, Tianqi, Kapur, Ravi, Lawrence, Donald P., Flaherty, Keith T., Sequist, Lecia V., Ramaswamy, Sridhar, Miyamoto, David T., Lawrence, Michael, Toner, Mehmet, Isselbacher, Kurt J., Maheswaran, Shyamala, Haber, Daniel A.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2018
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877960/
https://ncbi.nlm.nih.gov/pubmed/29453278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719264115
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