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Synthetic addiction extends the productive life time of engineered Escherichia coli populations

Bio-production of chemicals is an important driver of the societal transition toward sustainability. However, fermentations with heavily engineered production organisms can be challenging to scale to industrial volumes. Such fermentations are subject to evolutionary pressures that select for a wide...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rugbjerg, Peter, Sarup-Lytzen, Kira, Nagy, Mariann, Sommer, Morten Otto Alexander
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877936/
https://ncbi.nlm.nih.gov/pubmed/29463739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718622115
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